Article
Home Environment as a Source of Life-Threatening Azole-Resistant Aspergillus fumigatus in Immunocompromised Patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jan 2017
Lavergne Rose-Anne, Chouaki Taieb, Hagen Ferry, Toublanc Bénédicte, Dupont Hervé, Jounieaux Vincent, Meis Jacques F, Morio Florent, Le Pape Patrice
Abstract excerpt
A case of fatal aspergillosis due to a TR46/Y121F/T289A azole-resistant Aspergillus fumigatus is reported. Environmental investigations at the patient's residence led to the recovery of TR46/Y121F/T289A isolates, genotypically indistinguishable from the clinical isolate, supporting for the first time the direct role of household as potential source of azole-resistant invasive aspergillosis.
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