Article
Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer.
World journal of gastroenterology - 21 Sept 2016
da Silva Oliveira Kelly Cristina, Thomaz Araújo Taíssa Maíra, Albuquerque Camila Inagaki, Barata Gabriela Alcantara, Gigek Carolina Oliveira, Leal Mariana Ferreira, Wisnieski Fernanda, Rodrigues Mello Junior Fernando Augusto, Khayat André Salim, de Assumpção Paulo Pimentel, Rodriguez Burbano Rommel Mário, Smith Marília Cardoso, Calcagno Danielle Queiroz
Abstract excerpt
Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic miRNAs and downregulated tumour-suppressor miRNAs in this type of cancer. In this review, we provide an overview of the role of miRNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in...
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