Article
Breaking the Cycle: Estrous Variation Does Not Require Increased Sample Size in the Study of Female Rats.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2016
Dayton Alex, Exner Eric C, Bukowy John D, Stodola Timothy J, Kurth Theresa, Skelton Meredith, Greene Andrew S, Cowley Allen W
Abstract excerpt
Despite the striking differences between male and female physiology, female physiology is understudied. In response, the National Institutes of Health is promulgating new policies to increase the use of female organisms in preclinical research. Females are commonly believed to have greater variability than males because of the estrous cycle, but recent studies call this belief into question. Effects of estrous...
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