Article
Phylogenesys and homology modeling in Zika virus epidemic: food for thought.
Pathogens and global health - 1 Jan 2000
Angeletti Silvia, Lo Presti Alessandra, Giovanetti Marta, Grifoni Alba, Amicosante Massimo, Ciotti Marco, Alcantara Luiz-Carlos J, Cella Eleonora, Ciccozzi Massimo
Abstract excerpt
Zika virus (ZIKV) is an emerging Flavivirus that have recently caused an outbreak in Brazil and rapid spread in several countries. In this study, the consequences of ZIKV evolution on protein recognition by the host immune system have been analyzed. Evolutionary analysis was combined with homology modeling and T-B cells epitope predictions. Two separate clades, the African one with the Uganda sequence, as the...
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