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Article

Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection.

Virulence - 18 Aug 2017

Moreira Ana S, Mil-Homens Dalila, Sousa Sílvia A, Coutinho Carla P, Pinto-de-Oliveira Ana, Ramos Christian G, Dos Santos Sandra C, Fialho Arsénio M, Leitão Jorge H, Sá-Correia Isabel

Abstract excerpt

During long-term lung infection in cystic fibrosis (CF) patients, Burkholderia cenocepacia faces multiple selective pressures in this highly stressful and fluctuating environment. As a consequence, the initial infecting strain undergoes genetic changes that result in the diversification of genotypes and phenotypes. Whether this clonal expansion influences the pathogenic potential is unclear. The virulence...

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Identifiers

PMID: 27652671
DOI: 10.1080/21505594.2016.1237334
PMCID: PMC5626231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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