Article
Burkholderia cenocepacia phenotypic clonal variation during a 3.5-year colonization in the lungs of a cystic fibrosis patient.
Infection and immunity - 1 Jul 2011
Coutinho Carla P, de Carvalho Carla C C R, Madeira Andreia, Pinto-de-Oliveira Ana, Sá-Correia Isabel
Abstract excerpt
Chronic lung infection is the major cause of morbidity and premature mortality in cystic fibrosis (CF) patients. Bacteria of the Burkholderia cepacia complex are the most threatening pathogens in CF, and a better understanding of how these bacteria adapt to the CF airway environment and resist the host defense mechanisms and therapeutically administered antibiotics is crucial. To provide clues to the adaptive...
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