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Article

Long noncoding RNA <em>SPRY4-IT1</em> promotes malignant development of colorectal cancer by targeting epithelial&ndash;mesenchymal transition

1 Aug 2016

Abstract excerpt

The clinical significance and biological functions of long noncoding RNA SPRY4 intronic transcript 1 (SPRY4-IT1) in colorectal cancer (CRC) remain largely unclear. Herein, we are the first to report that the SPRY4-IT1 was significantly upregulated in CRC tissues, serum, and cells. Higher SPRY4-IT1 expression was markedly associated with advanced Tumor Node Metastasis (TNM) stage in a cohort of 84 CRC patients....

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Identifiers

PMID: 27621655
DOI: 10.2147/ott.s111794

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