Article
A rare variant in COL11A1 is strongly associated with adult height in Chinese Han population.
Journal of genetics and genomics = Yi chuan xue bao - 20 Sept 2016
Shen Changbing, Zheng Xiaodong, Gao Jing, Zhu Caihong, Ko Randy, Tang Xianfa, Yang Chao, Dou Jinfa, Lin Yan, Cheng Yuyan, Liu Lu, Xu Shuangjun, Chen Gang, Zuo Xianbo, Yin Xianyong, Sun Liangdan, Cui Yong, Yang Sen, Zhang Xuejun, Zhou Fusheng
Abstract excerpt
Human height is a highly heritable trait in which multiple genes are involved. Recent genome-wide association studies (GWASs) have identified that COL11A1 is an important susceptibility gene for human height. To determine whether the variants of COL11A1 are associated with adult and children height, we analyzed splicing and coding single-nucleotide variants across COL11A1 through exome-targeted sequencing and two...
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