Article
Effects of polycyclic aromatic compounds in fine particulate matter generated from household coal combustion on response to EGFR mutations in vitro.
Environmental pollution (Barking, Essex : 1987) - 1 Nov 2016
Ho Kin-Fai, Chang Chih-Cheng, Tian Linwei, Chan Chi-Sing, Musa Bandowe Benjamin A, Lui Ka-Hei, Lee Kang-Yun, Chuang Kai-Jen, Liu Chien-Ying, Ning Zhi, Chuang Hsiao-Chi
Abstract excerpt
Induction of PM2.5-associated lung cancer in response to EGFR-tyrosine kinase inhibitors (EGFR-TKI) remains unclear. Polycyclic aromatic hydrocarbons (PAHs) and their polar derivatives (oxygenated PAHs: OPAHs and azaarenes: AZAs) were characterized in fine particulates (PM2.5) emitted from indoor coal combustion. Samples were collected in Xuanwei (Yunnan Province), a region in China with a high rate of lung...
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