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Experimental Infection of Calves with Escherichia coli O104:H4 outbreak strain

7 Sept 2016

Abstract excerpt

In 2011, a severe outbreak of hemolytic-uremic syndrome was caused by an unusual, highly virulent enterohemorrhagic E. coli (EHEC) O104:H4 strain, which possessed EHEC virulence traits in the genetic background of human-adapted enteroaggregative E. coli. To determine magnitude of fecal shedding and site of colonization of EHEC O104:H4 in a livestock host, 30 (ten/strain) weaned calves were inoculated with 10(10)...

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PMID: 27600997
DOI: 10.1038/srep32812

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