Article
VDR and VDBP genes polymorphisms associated with susceptibility to tuberculosis in a Han Taiwanese population.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Oct 2016
Lee Shih-Wei, Chuang Tzu-Yi, Huang Hsiu-Han, Liu Chi-Wei, Kao Yung-Hsi, Wu Lawrence Shih-Hsin
Abstract excerpt
BACKGROUND: The active metabolite (1, 25-dihydroxycholecalciferol) of vitamin D (25-hydroxycholecalciferol) leads to the activation of macrophages and the deficiency of vitamin D seems to be involved in the risk of tuberculosis (TB). The effects of vitamin D are exerted by interaction with the vitamin D receptor (VDR) and vitamin D receptor binding protein (VDBP) may be influenced by polymorphisms in the VDR and...
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