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Article

Next-generation sequencing analysis of off-ladder alleles due to migration shift caused by sequence variation at D12S391 locus.

Legal medicine (Tokyo, Japan) - 1 Sept 2016

Fujii Koji, Watahiki Haruhiko, Mita Yusuke, Iwashima Yasuki, Miyaguchi Hajime, Kitayama Tetsushi, Nakahara Hiroaki, Mizuno Natsuko, Sekiguchi Kazumasa

Abstract excerpt

In short tandem repeat (STR) analysis, length polymorphisms are detected by capillary electrophoresis (CE). At most STR loci, mobility shift due to sequence variation in the repeat region was thought not to affect the typing results. In our recent population studies of 1501 Japanese individuals, off-ladder calls were observed at the D12S391 locus using PowerPlex Fusion in nine samples for allele 22, one sample...

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PMID: 27591542
DOI: 10.1016/j.legalmed.2016.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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