Article
Programmed cell death-ligand 1 expression in oral squamous cell carcinoma is associated with an inflammatory phenotype.
Pathology - 1 Oct 2016
Satgunaseelan Laveniya, Gupta Ruta, Madore Jason, Chia Noel, Lum Trina, Palme Carsten E, Boyer Michael, Scolyer Richard A, Clark Jonathan R
Abstract excerpt
Phase 2 clinical trials utilising novel anti-PD1/PD-L1 antibodies are being conducted in oral cavity squamous cell carcinoma (OSCC) patients. However, data regarding PD-L1 expression in OSCC is limited. The aim of this study was to characterise the PD-L1 immunohistochemical expression in OSCC and its association with clinicopathological factors. Clinicopathological review of 217 patients with OSCC was performed,...
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