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Article

Acute fatty liver of pregnancy: an update on mechanisms

4 Jul 2011

Abstract excerpt

Acute fatty liver of pregnancy (AFLP), characterized by hepatic microvesicular steatosis, is a sudden catastrophic illness occurring almost exclusively in the third trimester of pregnancy. Defective fatty acid oxidation in the fetus has been shown to be associated with this disease. Since the placenta has the same genetic makeup as the fetus and as AFLP patients generally recover following delivery, we...

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PMID: 27579101
DOI: 10.1258/om.2011.100071

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