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Article

Pathophysiology of fatty acid oxidation disorders.

Journal of inherited metabolic disease - 1 Oct 2010

Bennett M J

Abstract excerpt

Mitochondrial fatty acid oxidation represents an important pathway for energy generation during periods of increased energy demand such as fasting, febrile illness and muscular exertion. In liver, the primary end products of the pathway are ketone bodies, which are released into the circulation and provide energy to tissues that are not able to oxidize fatty acids such as brain. Other tissues, such as cardiac and...

Topics

Animals
Energy Metabolism
Fatty Acids
Genotype
Humans
Lipid Metabolism, Inborn Errors
Mitochondria
Mitochondrial Diseases
Oxidation-Reduction
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20824345
DOI: 10.1007/s10545-010-9170-y

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