Article
Complex Class 1 Integron Carrying qnrB62 and blaVIM-2 in a Citrobacter freundii Clinical Isolate.
Antimicrobial agents and chemotherapy - 1 Nov 2016
Lee Jae Jin, Kim Mi-Na, Park Kwang Seung, Lee Jung Hun, Karim Asad Mustafa, Park Moonhee, Kim Ji Hwan, Lee Sang Hee
Abstract excerpt
The coexistence of qnrB62 and blaVIM-2 was detected in a Citrobacter clinical isolate. The reduced fluoroquinolone susceptibility is attributable to qnrB62, mutations of quinolone-resistance-determining regions, and an efflux pump or pumps. The genetic context surrounding chromosomal qnrB62 was a novel complex class 1 integron (In1184::ISCR1::qnrB62) containing a unique gene array (blaVIM-2-aacA4'-8-gucD). An...
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