Article
QnrB9 in association with TEM-116 extended-spectrum beta-lactamase in Citrobacter freundii isolated from sewage effluent: first report from Italy.
Journal of chemotherapy (Florence, Italy) - 1 Aug 2010
Forcella C, Pellegrini C, Celenza G, Segatore B, Calabrese R, Tavio M M, Amicosante G, Perilli M
Abstract excerpt
The aim of the present study was to investigate the mechanism of quinolone and beta-lactam resistance in an isolate of Citrobacter freundii PC2/08 collected from sewage effluent from l'Aquila, Italy. QnrB-9 and bla(TEM-116 )were co-expressed in a large plasmid identified in C. freundi PC2/08 strain. Compared to TEM-1, TEM-116 showed two single mutations: V84I and A184V. The plPC2/08 plasmid conferred resistance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
