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The presence of a single MALDI-TOF mass spectral peak predicts methicillin resistance in staphylococci

7 Aug 2016

Abstract excerpt

The class A mec gene complex also carries the psm-mec gene. The psm-mec gene product can be detected as a peak near 2415m/z using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). The correlation of a 2415m/z peak with methicillin resistance (mecA carriage) in consecutive staphylococcal blood culture isolates was evaluated. A 2415±2.00m/z peak was observed in 37%...

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PMID: 27568365
DOI: 10.1016/j.diagmicrobio.2016.08.001

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