Article
Seizure Suppression by High Temperature via cAMP Modulation in Drosophila.
G3 (Bethesda, Md.) - 13 Oct 2016
Saras Arunesh, Tanouye Mark A
Abstract excerpt
Bang-sensitive (BS) Drosophila mutants display characteristic seizure-like activity (SLA) and paralysis after mechanical shock . After high-frequency electrical stimulation (HFS) of the brain, they generate robust seizures at very low threshold voltage. Here we report an important phenomenon, which effectively suppresses SLA in BS mutants. High temperature causes seizure suppression in all BS mutants (parabss1,...
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