Article
Whole genomic sequence analysis of Bacillus infantis: defining the genetic blueprint of strain NRRL B-14911, an emerging cardiopathogenic microbe.
BMC genomics - 22 Aug 2016
Massilamany Chandirasegaran, Mohammed Akram, Loy John Dustin, Purvis Tanya, Krishnan Bharathi, Basavalingappa Rakesh H, Kelley Christy M, Guda Chittibabu, Barletta Raúl G, Moriyama Etsuko N, Smith Timothy P L, Reddy Jay
Abstract excerpt
BACKGROUND: We recently reported the identification of Bacillus sp. NRRL B-14911 that induces heart autoimmunity by generating cardiac-reactive T cells through molecular mimicry. This marine bacterium was originally isolated from the Gulf of Mexico, but no associations with human diseases were reported. Therefore, to characterize its biological and medical significance, we sought to determine and analyze the...
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