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Article

Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophy.

BMC genomics - 22 Aug 2016

Brinkmeyer-Langford Candice, Balog-Alvarez Cynthia, Cai James J, Davis Brian W, Kornegay Joe N

Abstract excerpt

BACKGROUND: Duchenne muscular dystrophy (DMD) causes progressive muscle degeneration, cardiomyopathy and respiratory failure in approximately 1/5,000 boys. Golden Retriever muscular dystrophy (GRMD) resembles DMD both clinically and pathologically. Like DMD, GRMD exhibits remarkable phenotypic variation among affected dogs, suggesting the influence of modifiers. Understanding the role(s) of genetic modifiers of...

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Identifiers

PMID: 27549615
DOI: 10.1186/s12864-016-2948-z
PMCID: PMC4994242

Genes

DMD

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Source receipt: pubmed, retrieved 7 Sept 2026.

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