Article
The efficacy and safety of direct acting antiviral treatment and clinical significance of drug-drug interactions in elderly patients with chronic hepatitis C virus infection.
Alimentary pharmacology & therapeutics - 1 Oct 2016
Vermehren J, Peiffer K-H, Welsch C, Grammatikos G, Welker M-W, Weiler N, Zeuzem S, Welzel T M, Sarrazin C
Abstract excerpt
BACKGROUND: Direct antiviral therapies for chronic hepatitis C virus (HCV) infection have expanded treatment options for neglected patient populations, including elderly patients who are ineligible/intolerant to receive interferon (IFN)-based therapy. AIM: To investigate the efficacy, tolerability and potential for drug-drug interactions (DDIs) of IFN-free treatment in patients aged ≥65 years in a large...
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