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Article

Stem Cell Therapy for the Heart: Blind Alley or Magic Bullet?

Journal of cardiovascular translational research - 1 Dec 2016

Bruyneel Arne A N, Sehgal Apurv, Malandraki-Miller Sophia, Carr Carolyn

Abstract excerpt

When stressed by ageing or disease, the adult human heart is unable to regenerate, leading to scarring and hypertrophy and eventually heart failure. As a result, stem cell therapy has been proposed as an ultimate therapeutic strategy, as stem cells could limit adverse remodelling and give rise to new cardiomyocytes and vasculature. Unfortunately, the results from clinical trials to date have been largely...

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Identifiers

PMID: 27542008
DOI: 10.1007/s12265-016-9708-y
PMCID: PMC5153828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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