Article
How to mend a broken heart: adult and induced pluripotent stem cell therapy for heart repair and regeneration.
Drug discovery today - 1 Jun 2015
Wegener Marie, Bader Augustinus, Giri Shibashish
Abstract excerpt
The recently developed ability to differentiate primary adult stem cells and induced pluripotent stem cells (iPSCs) into cardiomyocytes is providing unprecedented opportunities to produce an unlimited supply of cardiomyocytes for use in patients with heart disease. Here, we examine the evidence for the preclinical use of such cells for successful heart regeneration. We also describe advances in the identification...
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