Article
Pretreatment serum levels of interferon-gamma-inducible protein-10 are associated with virologic response to telaprevir-based therapy.
Cytokine - 1 Dec 2016
Yamagiwa Yoko, Asano Mai, Kawasaki Youhei, Korenaga Masaaki, Murata Kazumoto, Kanto Tatsuya, Mizokami Masashi, Masaki Naohiko
Abstract excerpt
AIM: Telaprevir (TVR) remarkably improves the efficacy of interferon treatment for chronic hepatitis C. Interleukin-28B (IL28B) genotype and interferon-gamma-inducible protein-10 (IP-10) level predict virologic response to peg-interferon (Peg-IFN)/ribavirin (RBV) therapy. We aimed to investigate the usefulness of pretreatment serum IP-10 levels and IL28B genotyping in predicting sustained virologic response (SVR)...
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