Baseline factors and very early viral response (week 1) for predicting sustained virological response in telaprevir-based triple combination therapy for Japanese genotype 1b chronic hepatitis C patients: a multicenter study.

doi:10.1007/s00535-013-0918-7

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Article

Baseline factors and very early viral response (week 1) for predicting sustained virological response in telaprevir-based triple combination therapy for Japanese genotype 1b chronic hepatitis C patients: a multicenter study.

Journal of gastroenterology - 1 Nov 2014

Shimada Noritomo, Toyoda Hidenori, Tsubota Akihito, Ide Tatsuya, Takaguchi Koichi, Kato Keizo, Kondoh Masaki, Matsuyama Kazuhiro, Kumada Takashi, Sata Michio

Abstract excerpt

BACKGROUND: Genetic polymorphisms near Interleukin 28B (IL28B) (rs8099917) and a rapid virological response (RVR) have been reported as predictors for a sustained virological response (SVR) to telaprevir (TVR)-based triple combination therapy. However, the association between SVR and viral kinetics earlier than week 4 after initiation of therapy remains unclear. Thus, we evaluated the SVR prediction ability of...

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PMID: 24287582
DOI: 10.1007/s00535-013-0918-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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