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Article

Variations in T cell transcription factor gene structure and expression associated with the two disease forms of sheep paratuberculosis.

Veterinary research - 17 Aug 2016

Nicol Louise, Wilkie Hazel, Gossner Anton, Watkins Craig, Dalziel Robert, Hopkins John

Abstract excerpt

Two different forms of clinical paratuberculosis in sheep are recognised, related to the level of bacterial colonization. Paucibacillary lesions are largely composed of lymphocytes with few bacteria, and multibacillary pathology is characterized by heavily-infected macrophages. Analysis of cytokine transcripts has shown that inflammatory Th1/Th17 T cells are associated with development of paucibacillary pathology...

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Source

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Identifiers

PMID: 27530627
DOI: 10.1186/s13567-016-0368-3
PMCID: PMC4988036

Genes

GATA3
TBX21
RORA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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