RNA sequencing of transformed lymphoblastoid cells from siblings discordant for autism spectrum disorders reveals transcriptomic and functional alterations: Evidence for sex‐specific effects

Abstract excerpt

Genome-wide expression studies of samples derived from individuals with autism spectrum disorder (ASD) and their unaffected siblings have been widely used to shed light on transcriptomic differences associated with this condition. Females have historically been under-represented in ASD genomic studies. Emerging evidence from studies of structural genetic variants and peripheral biomarkers suggest that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autism Spectrum Disorder Research
• Share to Genetics and Neurodevelopmental Disorders
• Share to Virology and Viral Diseases