Article
Burkholderia pseudomallei Biofilm Promotes Adhesion, Internalization and Stimulates Proinflammatory Cytokines in Human Epithelial A549 Cells.
PloS one - 1 Jan 2016
Kunyanee Chanikarn, Kamjumphol Watcharaporn, Taweechaisupapong Suwimol, Kanthawong Sakawrat, Wongwajana Suwin, Wongratanacheewin Surasak, Hahnvajanawong Chariya, Chareonsudjai Sorujsiri
Abstract excerpt
Burkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis. Inhalational exposure leading to pulmonary melioidosis is the most common clinical manifestation with significant mortality. However, the role of B. pseudomallei biofilm phenotype during bacterial-host interaction remains unclear. We hypothesize that biofilm phenotype may play a role in such interactions. In this study, B....
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