Article
Early activation of MyD88-mediated autophagy sustains HSV-1 replication in human monocytic THP-1 cells
11 Aug 2016
Abstract excerpt
Autophagy is a cellular degradation pathway that exerts numerous functions in vital biological processes. Among these, it contributes to both innate and adaptive immunity. On the other hand, pathogens have evolved strategies to manipulate autophagy for their own advantage. By monitoring autophagic markers, we showed that HSV-1 transiently induced autophagosome formation during early times of the infection of...
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