Article
The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients.
Oncotarget - 13 Sept 2016
Gahete Manuel D, Rincón-Fernández David, Durán-Prado Mario, Hergueta-Redondo Marta, Ibáñez-Costa Alejandro, Rojo-Sebastián Alejandro, Gracia-Navarro Francisco, Culler Michael D, Casanovas Oriol, Moreno-Bueno Gema, Luque Raúl M, Castaño Justo P
Abstract excerpt
The truncated somatostatin receptor sst5TMD4 is associated with poor prognosis in breast cancer and increases breast cancer cell malignancy. Here, we examined the cellular/molecular mechanisms underlying this association, aiming to identify new molecular tools to improve diagnosis, prognosis or therapy. A gene expression array comparing sst5TMD4 stably-transfected MCF-7 cells and their controls (empty-plasmid)...
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