Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in rats

8 Aug 2016

Abstract excerpt

Radiation therapy is commonly used to treat cancer patients but exhibits adverse effects, including insufficiency fractures and bone loss. Epigenetic regulation plays an important role in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Here, we reported local bone changes after single-dose exposure to (137)CS irradiation in rats. Femur bone mineral density (BMD) and trabecular bone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Heterotopic Ossification and Related Conditions

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27499068
DOI: 10.1038/srep31318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased EZH2 and decreased osteoblastogenesis during local irradiation-induced bone loss in ratsPMID 27499068Read ↗

Intracellular Delivery of Bone Nanoparticles to Mitigate Irradiation-Induced Damage in Bone Marrow Mesenchymal Stem CellsSemantic proximity Read ↗

Irradiation alters the differentiation potential of bone marrow mesenchymal stem cellsSemantic proximity Read ↗

Epigenetic therapy attenuates oxidative stress in BMSCs during ageingSemantic proximity Read ↗

Ferulic acid combined with skeletal stem cells to repair irradiated bone defectSemantic proximity Read ↗

Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ipSemantic proximity Read ↗

Effects of irradiation on growth and differentiation-related gene expression in osteoblasts.Semantic proximity Read ↗

Effects of Ionizing Radiation on Proliferation and Differentiation of Osteoblast-like CellsSemantic proximity Read ↗

Low‑dose X‑ray irradiation induces morphological changes and cytoskeleton reorganization in osteoblastsSemantic proximity Read ↗

Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male MiceSemantic proximity Read ↗

Ezh2 mediates epigenetic regulation of osteoclastogenesis and bone remodeling in miceSemantic proximity Read ↗

RUNX2: A Master Bone Growth Regulator That May Be Involved in the DNA Damage ResponseSemantic proximity Read ↗

Zoledronate Attenuates Accumulation of DNA Damage in Mesenchymal Stem Cells and Protects Their FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.