Article
Heterogeneity of anti-U demonstrable by the use of papain-treated red cells.
Transfusion - 1 Jan 2000
Issitt P D, Marsh W L, Wren M R, Theuriere M, Mueller K
Abstract excerpt
When red cells (RBCs) are treated with papain, one form of the U antigen, which we have named UPS (U papain-sensitive), is almost completely removed or denatured. A second form, UPR (U papain-resistant), remains unaltered on the treated RBCs. Tests on 42 examples of anti-U showed that two contained only anti-UPS, 19 contained only -UPR, and 21 contained separable -UPS and -UPR. In those sera containing both...
Topics
- Adsorption
- Adult
- Blood Group Antigens
- Blood Grouping and Crossmatching
- Coombs Test
- Humans
- Indicators and Reagents
- Isoantibodies
- MNSs Blood-Group System
- Male
- Papain
- Phenotype