Article
A clinically significant anti-N in a patient whose red cells were negative for N and U antigens.
Transfusion - 1 Jan 2000
Ballas S K, Dignam C, Harris M, Marcolina M J
Abstract excerpt
A patient with sickle cell anemia had M+N-S-s-U-phenotype and developed anti-E, anti-U, and anti-N after multiple transfusions. The anti-N was IgG, showed positive red cell mononuclear phagocyte assay, caused shortened survival of 51Cr-labeled N+ red cells, and incited a delayed hemolytic transfusion reaction. The anti-U also caused decreased survival of U+ cells. The serological findings indicated that the...
Topics
- Blood Grouping and Crossmatching
- Chromium Radioisotopes
- Erythrocyte Aging
- Humans
- MNSs Blood-Group System
- Male
- Middle Aged
- Phenotype
- Transfusion Reaction