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A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation

4 Aug 2016

Abstract excerpt

High-throughput technologies revealed new categories of genes, including the long noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease; however, the role of lncRNAs in the ulcerative colitis (UC) has not been evaluated. Gene expression profiling was used to develop lncRNA signatures in UC samples. Jurkat T cells were activated by PMA/ionomycin subsequently interferon-γ (IFNG) and tumor necrosis...

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PMID: 27492330
DOI: 10.1152/ajpgi.00212.2016

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