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Electroporation by subnanosecond pulses

3 May 2016

Abstract excerpt

Electropermeabilization of cell membranes by micro- and nanosecond-duration stimuli has been studied extensively, whereas effects of picosecond electric pulses (psEP) remain essentially unexplored. We utilized whole-cell patch clamp and Di-8-ANEPPS voltage-sensitive dye measurements to characterize plasma membrane effects of 500 ps stimuli in rat hippocampal neurons (RHN), NG108, and CHO cells. Even a single...

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PMID: 27482547
DOI: 10.1016/j.bbrep.2016.05.002

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