Article
Five known tagging DLL3 SNPs are not associated with congenital scoliosis: A case-control association study in a Chinese Han population.
Medicine - 1 Jul 2016
Yang Yong, Wang Bing-Qiang, Wu Zhi-Hong, Zhang Hai-Yan, Qiu Gui-Xing, Shen Jian-Xiong, Zhang Jian-Guo, Zhao Yu, Wang Yi-Peng, Fei Qi
Abstract excerpt
Genetic etiology hypothesis is widely accepted in the development of congenital scoliosis (CS). The delta-like 3 (DLL3) gene, a member of the Notch signaling pathway, was implicated to contribute to human CS. In this study, a case-control association study was conducted to determine the association of single nucleotide polymorphism (SNP) in the DLL3 gene with CS in a Chinese Han Population. Five known tagging...
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