Article
Identification of source and sink populations for the emergence and global spread of the East-Asia clone of community-associated MRSA.
Genome biology - 26 Jul 2016
Ward Melissa J, Goncheva Mariya, Richardson Emily, McAdam Paul R, Raftis Emma, Kearns Angela, Daum Robert S, David Michael Z, Lauderdale Tsai Ling, Edwards Giles F, Nimmo Graeme R, Coombs Geoffrey W, Huijsdens Xander, Woolhouse Mark E J, Fitzgerald J Ross
Abstract excerpt
BACKGROUND: Our understanding of the factors influencing the emergence, dissemination and global distribution of epidemic clones of bacteria is limited. ST59 is a major epidemic clone of community-associated MRSA in East Asia, responsible for extensive morbidity and mortality, but has a much lower prevalence in other parts of the world. The geographic origin of ST59 and its international routes of dissemination...
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