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Article

Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma

22 Jul 2016

Abstract excerpt

BACKGROUND: Epigenetic events mediated by methylation and histone modifications have been associated with the development of metastasis in patients with uveal melanoma. The role of epigenetic events mediated by microRNA (miR) is less clear. Tumor and plasma miR expression was examined in patients with primary uveal melanoma with tumor monosomy-3, a predictor of metastasis. RESULTS: miR profiling of tumors by...

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PMID: 27453764
DOI: 10.1186/s13148-016-0243-0

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