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Article

Indel analysis by droplet digital PCR: a sensitive method for DNA mixture detection and chimerism analysis.

International journal of legal medicine - 1 Jan 2017

Santurtún Ana, Riancho José A, Arozamena Jana, López-Duarte Mónica, Zarrabeitia María T

Abstract excerpt

Several methods have been developed to determinate genetic profiles from a mixed samples and chimerism analysis in transplanted patients. The aim of this study was to explore the effectiveness of using the droplet digital PCR (ddPCR) for mixed chimerism detection (a mixture of genetic profiles resulting after allogeneic hematopoietic stem cell transplantation (HSCT)). We analyzed 25 DNA samples from patients who...

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Identifiers

PMID: 27448113
DOI: 10.1007/s00414-016-1422-4

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