Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-149 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1

1 Jan 2016

Abstract excerpt

BACKGROUND/AIMS: Previously, we have shown that microRNA (miR)-149 suppresses the migration and invasion of colorectal cancer (CRC) cells by targeting forkhead box transcription factor (FOXM1). However, the roles of miR-149 in the chemoresistance of CRC cells to 5-Fluorouracil (5-FU) is unclear. The aim of this study is to investigate whether miR-149 targets FOXM1 to regulate the 5-FU resistance of CRC. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to FOXO transcription factor regulation
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27415661
DOI: 10.1159/000445653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-149 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1PMID 27415661Read ↗

FOXM1 evokes 5-fluorouracil resistance in colorectal cancer depending on ABCC10Semantic proximity Read ↗

miR-149 reverses cisplatin resistance of gastric cancer SGC7901/DDP cells by targeting FoxM1Semantic proximity Read ↗

Decreased expression of miR‑3135b reduces sensitivity to 5‑fluorouracil in colorectal cancer by direct repression of PIM1Semantic proximity Read ↗

Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acidsSemantic proximity Read ↗

RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathwaySemantic proximity Read ↗

miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4Semantic proximity Read ↗

Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer CellsSemantic proximity Read ↗

The Tumor Suppressive Role of MiRNA-509-5p by Targeting FOXM1 in Non-Small Cell Lung CancerSemantic proximity Read ↗

FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expressionSemantic proximity Read ↗

MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signalingSemantic proximity Read ↗

The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer CellsSemantic proximity Read ↗

miR-199b-3p contributes to acquired resistance to cetuximab in colorectal cancer by targeting CRIM1 via Wnt/β-catenin signalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.