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Maternal iron status during pregnancy compared with neonatal iron status better predicts placental iron transporter expression in humans

11 Jul 2016

Abstract excerpt

The placenta richly expresses nonheme and heme Fe transport proteins. To address the impact of maternal and neonatal Fe status and hepcidin on the regulation of these proteins, mRNA expression and protein abundance of nonheme and heme Fe transport proteins were evaluated in placental tissue from 154 adolescents. Regression analyses found maternal Fe status was significantly associated with multiple placental...

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PMID: 27402672
DOI: 10.1096/fj.201600069r

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