Article
Limited Contribution of DNA Methylation Variation to Expression Regulation in Arabidopsis thaliana.
PLoS genetics - 1 Jul 2016
Meng Dazhe, Dubin Manu, Zhang Pei, Osborne Edward J, Stegle Oliver, Clark Richard M, Nordborg Magnus
Abstract excerpt
The extent to which epigenetic variation affects complex traits in natural populations is not known. We addressed this question using transcriptome and DNA methylation data from a sample of 135 sequenced A. thaliana accessions. Across individuals, expression was significantly associated with cis-methylation for hundreds of genes, and many of these associations remained significant after taking SNP effects into...
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