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Article

Gene body methylation regulates gene expression and mediates phenotypic diversity in natural Arabidopsis populations.

Nature plants - 1 Oct 2025

Shahzad Zaigham, Hollwey Elizabeth, Moore Jonathan D, Choi Jaemyung, Cassin-Ross Gaëlle, Rouached Hatem, Robinson Matthew R, Zilberman Daniel

Abstract excerpt

Genetic variation is generally regarded as a prerequisite for evolution. In principle, epigenetic information inherited independently of DNA sequence can also enable evolution, but whether this occurs in natural populations is unknown. Here we show that single-nucleotide and epigenetic gene body DNA methylation (gbM) polymorphisms explain comparable amounts of expression variance in Arabidopsis thaliana...

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Identifiers

PMID: 40940427
DOI: 10.1038/s41477-025-02108-4
PMCID: PMC12537493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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