Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta

1 Jul 2016

Abstract excerpt

It is widely accepted that diabetes mellitus impairs placental development, but the mechanism by which the disease operates to impair development remains controversial. In this study, we demonstrated that pregestational diabetes mellitus (PGDM)-induced defects in placental development in mice are mainly characterized by the changes of morphological structure of placenta. The alteration of differentiation-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Gestational Diabetes Research and Management
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27383629
DOI: 10.1098/rsob.160064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placentaPMID 27383629Read ↗

Oxidative Stress in Placenta: Health and DiseasesSemantic proximity Read ↗

Disruption of Placental Homeostasis Leads to PreeclampsiaSemantic proximity Read ↗

Mechanism of Placenta Damage in Gestational Diabetes Mellitus by Investigating TXNIP of Patient Samples and Gene Functional Research in Cell LineSemantic proximity Read ↗

Autophagy regulates abnormal placentation induced by folate deficiency in miceSemantic proximity Read ↗

DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsiaSemantic proximity Read ↗

Gestational diabetes mellitus affects placental iron homeostasis: Mechanism and clinical implicationsSemantic proximity Read ↗

Placental autophagy failure: A risk factor for preeclampsiaSemantic proximity Read ↗

Metformin ameliorates gestational diabetes mellitus via inhibiting ferroptosis of trophoblasts through the Nrf2/HO-1 signaling pathwaySemantic proximity Read ↗

Role of DRAM1 in mitophagy contributes to preeclampsia regulation in miceSemantic proximity Read ↗

Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity.Semantic proximity Read ↗

Human umbilical cord mesenchymal stem cells restores mTOR-mediated autophagy homeostasis to alleviate placental injury and improve pregnancy outcomes in preeclampsiaSemantic proximity Read ↗

When autophagy meets placenta development and pregnancy complicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.