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Article

Placental autophagy failure: A risk factor for preeclampsia

16 Sept 2020

Abstract excerpt

Hypertensive disorders of pregnancy, including preeclampsia, directly affect maternal and perinatal morbidity and mortality. As the pathophysiology of preeclampsia is multi-factorial and has been studied using different approaches, we have demonstrated that impaired autophagy is an intertwined risk factor for preeclampsia. This concept has been verified in both in vitro and in vivo experiments. Autophagy is...

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PMID: 32939889
DOI: 10.1111/jog.14489

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