Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A CD24‐p53 axis contributes to African American prostate cancer disparities

13 Mar 2020

Abstract excerpt

Abstract Background Using a functional analysis of prostate cancer cells, we found a CD24‐dependent inactivation of mutant p53, but the clinical significance of this observation remained uncertain. Here, we validated these results with samples of human prostate cancer and explored the role of a CD24‐p53 axis in racial disparities of prostate cancer. Methods Samples of formalin‐fixed, paraffin‐embedded prostate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Prostate Cancer Diagnosis and Treatment
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32168400
DOI: 10.1002/pros.23973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A CD24‐p53 axis contributes to African American prostate cancer disparitiesPMID 32168400Read ↗

CD24 and Mutant p53: Emerging Therapeutic Targets in Prostate Cancer Progression.Semantic proximity Read ↗

Silencing of CD24 Enhances the PRIMA-1–Induced Restoration of Mutant p53 in Prostate Cancer CellsSemantic proximity Read ↗

Racial Disparity in Utilizing Genetic Testing for Personalized Care of Prostate CancerSemantic proximity Read ↗

CD24 is a genetic modifier for risk and progression of prostate cancer.Semantic proximity Read ↗

Precision medicine targets for prostate cancers in African American menSemantic proximity Read ↗

Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation.Semantic proximity Read ↗

Racial disparities in prostate cancer: a molecular perspective.Semantic proximity Read ↗

Minireview: the molecular and genomic basis for prostate cancer health disparities.Semantic proximity Read ↗

CDKN1B Deletions are Associated with Metastasis in African American Men with Clinically Localized, Surgically Treated Prostate CancerSemantic proximity Read ↗

Prostate cancer in men of African origin.Semantic proximity Read ↗

Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: the Flint Men's Health Study.Semantic proximity Read ↗

Racial disparity in prostate cancer: an outlook in genetic and molecular landscapeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.