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Article

Biology of lung cancer: genetic mutation, epithelial-mesenchymal transition, and cancer stem cells.

General thoracic and cardiovascular surgery - 1 Sept 2016

Aoi Takashi

Abstract excerpt

At present, most cases of unresectable cancer cannot be cured. Genetic mutations, EMT, and cancer stem cells are three major issues linked to poor prognosis in such cases, all connected by inter- and intra-tumor heterogeneity. Issues on inter-/intra-tumor heterogeneity of genetic mutation could be resolved with recent and future technologies of deep sequencers, whereas, regarding such issues as the "same genome,...

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Identifiers

PMID: 27376535
DOI: 10.1007/s11748-016-0682-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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