Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages

29 Jun 2016

Abstract excerpt

Triggering antimicrobial mechanisms in macrophages infected with intracellular pathogens, such as mycobacteria, is critical to host defense against the infection. To uncover the unique and shared antimicrobial networks induced by the innate and adaptive immune systems, gene expression profiles generated by RNA sequencing (RNAseq) from human monocyte-derived macrophages (MDMs) activated with TLR2/1 ligand...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to S100 Proteins and Annexins
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27355424
DOI: 10.1371/journal.ppat.1005705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human MacrophagesPMID 27355424Read ↗

Genome-Wide Screening of mRNA Expression in Leprosy PatientsSemantic proximity Read ↗

The cellular architecture of the antimicrobial response network in human leprosy granulomasSemantic proximity Read ↗

A new paradigm for leprosy diagnosis based on host gene expression Insights from leprosy lesions transcriptomicsSemantic proximity Read ↗

A new paradigm for leprosy diagnosis based on host gene expressionSemantic proximity Read ↗

Use of Genetic Profiling in Leprosy to Discriminate Clinical Forms of the DiseaseSemantic proximity Read ↗

The role of S100A9 in the progression of tuberculosisSemantic proximity Read ↗

Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy GranulomasSemantic proximity Read ↗

The immune-suppressive landscape in lepromatous leprosy revealed by single-cell RNA sequencingSemantic proximity Read ↗

Large-Scale Gene Expression Signatures Reveal a Microbicidal Pattern of Activation in Mycobacterium leprae-Infected Monocyte-Derived Macrophages With Low Multiplicity of Infection.Semantic proximity Read ↗

Mycobacterial infection induces a specific human innate immune response.Semantic proximity Read ↗

Gene Association with Leprosy: A Review of Published DataSemantic proximity Read ↗

<i>Mycobacterium leprae</i> and host immune transcriptomic signatures for reactional states in leprosySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.