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Article

Iron-depletion promotes mitophagy to maintain mitochondrial integrity in pathogenic yeast Candida glabrata.

Autophagy - 2 Aug 2016

Nagi Minoru, Tanabe Koichi, Nakayama Hironobu, Ueno Keigo, Yamagoe Satoshi, Umeyama Takashi, Ohno Hideaki, Miyazaki Yoshitsugu

Abstract excerpt

Candida glabrata, a haploid budding yeast, is the cause of severe systemic infections in immune-compromised hosts. The amount of free iron supplied to C. glabrata cells during systemic infections is severely limited by iron-chelating proteins such as transferrin. Thus, the iron-deficiency response in C. glabrata cells is thought to play important roles in their survival inside the host's body. In this study, we...

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Identifiers

PMID: 27347716
DOI: 10.1080/15548627.2016.1183080
PMCID: PMC4968229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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